Photo: Pamela Smith / Getty Images Sport / Getty Images
The New York Knicks are heavy 10.5-point favorites heading into Game 2 of the second round of the NBA Playoffs against the Philadelphia 76ers at Madison Square Garden on Wednesday, starting at 7 p.m. ET on ESPN. The Knicks have a 1-0 series lead.
Watch the NBA, other live sports and more on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Use our link to sign up.
Listen to the game on ESPN New York
76ers vs. Knicks Predictions for Wednesday
Our computer projections model for this game expects a final tally of Knicks 119, 76ers 109.
- Moneyline Pick: Knicks (-448)
- Total Pick: Over 215 (computer predicts 228.1 points)
- Pick ATS: 76ers (+10.5)
Recent 76ers vs. Knicks Matchups
| Date | Favorite | Spread | Total | Favorite Moneyline | Underdog Moneyline | Result |
|---|---|---|---|---|---|---|
| 5/4/2026 | Knicks | -7.5 | 212.5 | -289 | +233 | 137-98 NY |
| 2/11/2026 | Knicks | -2.5 | 225.5 | -134 | +113 | 138-89 NY |
| 1/24/2026 | 76ers | -1.5 | 226.5 | -115 | -104 | 112-109 NY |
| 1/3/2026 | Knicks | -3.5 | 233.5 | -170 | +143 | 130-119 PHI |
| 12/19/2025 | Knicks | -6.5 | 230.5 | -249 | +203 | 116-107 PHI |
| 4/1/2025 | Knicks | -13.5 | 220 | -935 | +613 | 105-91 NY |
| 2/26/2025 | Knicks | -8.5 | 227.5 | -352 | +280 | 110-105 NY |
| 1/15/2025 | Knicks | -5.5 | 220 | -216 | +178 | 125-119 NY |
| 11/12/2024 | Knicks | -3.5 | 213 | -163 | +136 | 111-99 NY |
Knicks 2025-26 Betting Trends
- New York has gone 43-39-0 ATS this season.
- When they have played as at least 10.5-point favorites this season, the Knicks are 11-7 against the spread.
- A total of 37 of New York's 82 games with a set total have hit the over (45.1%).
- This season, the Knicks have been favored 64 times and won 46, or 71.9%, of those games.
- New York has a record of 15-3, a 83.3% win rate, when it's favored by -448 or more by oddsmakers this season.
76ers 2025-26 Betting Trends
- Philadelphia's ATS record is 41-41-0 this season.
- The 76ers are 0-6 against the spread when an underdog by 10.5 points or greater this season.
- The teams have combined to hit the over in 41 of Philadelphia's 82 games with a set total.
- The 76ers have won 11 of the 36 games they were the underdog on the moneyline this season (30.6%).
- Philadelphia has not yet won a game when entering as a moneyline underdog with odds of +347 or longer in six chances.
Looking for NBA tickets? Head to StubHub today and see your team live.
76ers vs. Knicks Injury Report
Knicks
Knicks: None
76ers
76ers:
Joel Embiid: Probable (Ankle)
76ers vs. Knicks Game Time and TV Channel
- Game day: Wednesday, May 6, 2026
- Game time: 7 p.m. ET
- TV channel: ESPN
- Location: New York City, New York
- Arena: Madison Square Garden
Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason.