Big Ten foes meet when the No. 2 Indiana Hoosiers (9-0) and the Penn State Nittany Lions (3-5) square off on Saturday, November 8, 2025 at West Shore Home Field at Beaver Stadium.
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Indiana vs. Penn State Matchup Info
- Game date: Saturday, November 8, 2025
- Game time: 12 p.m. ET
- Location: University Park, Pennsylvania
- Venue: West Shore Home Field at Beaver Stadium
- TV channel: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Indiana vs. Penn State Odds and Prediction
- Spread favorite: Hoosiers (-14.5)
- Moneyline: Hoosiers (-699), Nittany Lions (+500)
- Total: 48.5 points
- Pick ATS: Indiana (-14.5)
- Pick OU: Over (48.5)
- Prediction: Indiana 40, Penn State 14
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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Indiana vs. Penn State Betting Records and Insights
- Indiana has put together a 6-3-0 record against the spread this season.
- Penn State has covered just once in eight chances against the spread this year.
- The Hoosiers have been favored by 14.5 points or more six times this season, and covered the spread in four of those games.
- The Nittany Lions have not covered the spread when an underdog by 14.5 points or more this year (in one opportunity).
- Indiana games have gone over the point total six out of nine times this season.
- Penn State games have gone over the point total six out of eight times this year.