Eagles vs. Chiefs Week 2 Predictions, Odds and Stats

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The Philadelphia Eagles are expected to come out on top in their game versus the Kansas City Chiefs at 4:25 p.m. ET on Sunday, Sept. 14, according to our computer projection model. If you're seeking additional projections on the final score, spread, and point total, we list those numbers below.

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Eagles vs. Chiefs Game Info and TV Channel

  • When: Sunday, September 14, 2025 at 4:25 p.m. ET
  • Where: GEHA Field at Arrowhead Stadium in Kansas City, Missouri
  • TV: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Eagles vs. Chiefs Odds and Betting Info

  • Spread favorite: Eagles (-1.5)
  • Moneyline: Eagles (-122), Chiefs (+102)
  • Total: 47 points

Eagles vs. Chiefs Prediction

  • Pick ATS: Chiefs (+1.5)
  • Pick OU: Under (47)

Prediction:

Eagles 22 - Chiefs 21

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    Eagles vs. Chiefs Betting Insights (2024 Stats)

    • The Eagles won 11 games against the spread last season, failing to cover six times.
    • The Chiefs put together a 7-9-1 ATS record last year.
    • When playing as at least 1.5-point favorites last season, Philadelphia had an ATS record of 8-5.
    • Kansas City was an underdog by 1.5 points or more three times last year, and covered the spread in one of those contests.
    • Eagles games went over the point total seven out of 17 times last season.
    • The Chiefs and their opponent combined to go over the point total seven out of 17 times last year.

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