The Georgetown Hoyas have not won a Big East game since their surprising run to the 2021 Big East tournament title.
Patrick Ewing's team is 0-9 in league play this season and it comes into Tuesday with a 29-game losing streak in conference play.
So why even remotely consider betting on Georgetown to win outright?
Because Tuesday presents the last real opportunity for the Hoyas to end the streak. DePaul is the only other Big East team ranked outside the KenPom Top 100 and the Hoyas only lost by seven points to the Blue Demons in their first meeting.
A Georgetown victory is far from guaranteed these days, but if there was a spot for it to happen, it would occur at home versus DePaul.
Tuesday College Basketball Picks
Overall Record: 67-71-5 (0-5 Monday - Yikes!)
DePaul at Georgetown (+110) (Over 148) (7 p.m. ET, FS1)
Georgetown's best chance to end its two-year, 29-game Big East losing streak comes on Tuesday.
DePaul is the second-worst team in the Big East and it has not fared well away from Chicago this season.
The Blue Demons are 0-4 in Big East road games with an average margin of defeat of 12.75. They also scored 45 points in a road loss to Northwestern and fell by 11 at Duquense at the end of nonconference play.
Georgetown played decent basketball in the last week, as it pushed Villanova to the brink and scored 82 points against Xavier.
Patrick Ewing can take some positives from those two games and parlay them into a home win to at least bring something positive to the program that has suffered immensely over the last 22 months.
The surest thing from this matchup is the potential for points. Each team allows over 74 points per game. It will not be a high quality game, but at the bare minimum, it will be entertaining.
Notre Dame at NC State (-8) (7 p.m. ET, ACC Network)
Notre Dame is a dead team walking.
The Irish looked atrocious in double-digit losses to Florida State and Boston College, who share the ACC basement with them this season. Notre Dame conceded over 75 points in five of its last seven games.
Mike Brey's team should be one of the most popular sides to fade over the next six-to-eight weeks. It should struggle against on Tuesday versus NC State.
The Wolfpack average just under 10 more points per game than the Irish and they average 7.1 more rebounds per contest. They will be far more aggressive on the floor than their visitors.
Kevin Keatts' Wolfpack can also take away Notre Dame's top offensive strength. The Irish are 32nd on KenPom in three-point offense. NC State is 33rd in three-point defense.
LSU at Arkansas (-12.5) (7 p.m. ET, ESPN2)
Arkansas is in the process of rediscovering its groove.
The Razorbacks ended a four-game losing streak on on Saturday with a 12-point win over Ole Miss and now they get to torture a struggling LSU offense.
LSU scored 56 and 49 points in its last two games against Tennessee and Auburn. The Tigers will struggle to put up points again on Tuesday.
Arkansas held seven of its nine opponents at home under 60 points. Only Missouri posted a total over 65 points inside Bud Walton Arena.
That is a bad sign for a LSU offense that comes in averaging 67.9 points per game.
Miami (-3) at Florida State (7 p.m. ET, ESPNU)
I got irrationally excited when I saw Miami as this low of a favorite in Tallahassee.
The Hurricanes can use Tuesday's rivalry contest with Florida State as a bounce-back spot after a tough two-point road loss to Duke on Saturday.
Miami averages 8.1 more points and shoots 3.4 percent better than the Seminoles, who struggled from the start this season.
The Hurricanes are a far better team than the Seminoles and I believe that shows over 40 minutes.
Georgia Tech at Clemson (-10.5) (9 p.m. ET, ACC Network)
Clemson can hit cruise control in the ACC over the next three games.
The Tigers survived a tough two-game stretch against Duke and Virginia Tech and now it gets a run against three of the conference's worst programs, starting with Georgia Tech on Tuesday.
Georgia Tech suffered four double-digit defeats in its last five ACC games. The Yellow Jackets already lost to Clemson by 11 points at the start of ACC play.
The 24th-ranked Tigers need to pad their on top of the ACC, and win in style to improve their NCAA tournament seed, with two early February games against Miami and UNC on the horizon.
North Carolina at Syracuse (Over 150.5) (9 p.m. ET, ESPN)
North Carolina and Syracuse both average over 75 points per game and give up over 70 points per game.
The two ACC squads also shoot over 45 percent from the field, so that feels like the perfect formula for the over to hit in Syracuse on Tuesday night.